StopsNausea! contains a compound called CBDA which scientists have found to be extremely effective at reducing nausea. The CBDA activates neural cells in the brain that govern the sense of nausea. Hemp produces hundreds of different compounds, but hemp flowers make more CBDA than anything else. CBDA stands for cannabidiolic acid.
StopsNausea! contains powdered hemp and powdered ginger root. The hemp contains the CBDA, and ginger root also provides a time-honored herbal remedy to reduce queasiness.
What does CBDA do? CBDA sticks to a protein on the membrane of certain neurons. When the CBDA sticks to the protein, the protein changes shape and allows ions to enter the interior of the neuron. When the ions enter, an electrical polarization changes that cell’s behavior. These neuron cells live in loops or circuits that allow electrical signals to pass from one cell to another.
While neuron cells can pass electrical signals to one another, the cells do part of the signaling process using chemicals called neurotransmitters. At the end of one neuron, the electrical impulse causes neurotransmitters to be released. The next cell in the line has proteins called receptors. The secreted neurotransmitters stick or bind to receptor proteins on the next cell, and this causes a change in the protein shape. This change in shape can then cause the electrical signal to start up in that next cell.
Hemp flowers make CBDA and other cannabinoids in tiny glands called trichomes. Cannabinoids mimic molecules that animals normally use for biochemical equilibrium, which is also known as homeostasis. Humans have used cannabinoids for more than 5000 years for a broad assortment of medical benefits. Among those benefits is the treatment of nausea.
As scientists developed cancer treatments, chemotherapy patients found the treatments caused nausea. Many patients reported reduction in the nausea by smoking cannabis. In the 1970’s, oncologists found the same benefits were obtained with synthetic THC, however, patients had to tolerate the high caused by THC.
In 2013, research conducted by E. M. Rock and L. A. Parker confirmed the efficacy of CBDA on nausea. CBDA comes from hemp while THC comes from marijuana. Remarkably, the research found that CBDA was better than a hundred times more effective in controlling nausea compared to CBD or THC. This may be due to the CBDA fitting very snugly into the receptor protein. Chemists can convert CBDA into CBD which has its own beneficial effects. CBDA may also act to reduce anxiety as CBD does.
In summary, StopsNausea contains CBDA and other compounds that act on the neurons that control the feeling of nausea in the brain. ///
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